Medication Dispensary Hazardous Drugs Within the VTH

* This item is not routinely stocked in the Medication Dispensary and will be procured upon request.

Table 1 (Group 1): Drugs that have MSHI in the package insert and/or meet the NIOSH definition of a hazardous drug and one or more of the following criteria: are classified by the NTP as “known to be a human carcinogen”, or are classified by IARC as Group 1, “carcinogenic to humans” or Group 2A, “probably carcinogenic to humans.

Azathioprine

Carboplatin

*Chlorambucil

Chloramphenicol

*Cisplatin

Cyclophosphamide

Cyclosporine (Cyclavance/Atopica) (Optimmune Ophthalmic Ointment)

Cytarabine (Cytosar)

Dacarbazine

Daunorubicin

Dexrazoxane

Doxorubicin

Epirubicin

*Fluorouracil

Gemcitabine

Imatinib (Gleevec)

Lomustine (CCNU)

Mitomycin

Mitoxantrone

Mycophenolate mofetil

Procarbazine

Rabacfosadine (Tanovea)

Temozolomide

Toceranib (Palladia)

Vinblastine

Vincristine

Vinorelbine

Table 2 (Group 2): Drugs that meet the NIOSH definition of a hazardous drug and do not have MSHI, are not classified by NTP as “known to be a human carcinogen,” and are not classified by IARC as Group 1, “carcinogenic to humans,” or Group 2A, “probably carcinogenic to humans.” (Some may also have adverse developmental and/or reproductive effects.)

Altrenogest (Regu-Mate)

Apomorphine

*Chorionic Gonadotropin

DMSO (Dimethyl Sulfoxide)

*Estradiol

Fluconazole

Fluocinolone acetonide (Synotic) Otic Solution

Fosphenytoin

*Histrelin

Leflunomide

Lutalyse (Dinoprost Tromethamine)

Methimazole

Misoprostol

Oclacitinib (Apoquel)

*Olaparib

Oxytocin

Pergolide

*Sirolimus

Spironolactone

Tacrolimus (Ophthalmic Solution/Suspension)

Trilostane (Vetoryl)

Voriconazole

Tylosin

Zoledronic Acid (Zometa)

Zonisamide

 

Reference: NIOSH List of Hazardous Drugs in Healthcare Settings, 2024

 

Definitions (if applicable)

• IARC: International Agency for Research on Cancer
• MSHI: Manufacturer’s Special Handling Information
• NIOSH: National Institute for Occupational Safety and Health
• NTP: National Toxicology Program