Canvas allows you to create many different quiz question types. You can create a question for students that requires a file upload and can be used for PDFs, images, audio files, video files, etc. This question type requires manual grading and accepts one file per question. The following contains information on how to create a file upload quiz question: https://community.canvaslms.com/t5/Instructor-Guide/How-do-I-create-a-File-Upload-quiz-question/ta-p/652