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NMR - Mnova installation instructions

Installation and troubleshooting guide for installing the NMR Mnova software

23 June 2025

To: All Students, Staff, and Faculty of the UIUC Campus

Topic: Mnova NMR Software Full Version Available Free to All Campus Users

Dear NMR Users: Mnova NMR data analysis software is available free to everyone on the campus of the U. of Illinois at Urbana-Champaign. All students, staff, and faculty are eligible, and all you need is your net ID and password. This is a perpetual license package good through version 15.0.1 and any updates that occur through 25 Apr 2025. The 5-license package will continue to work perpetually, but might expire 90 days after leaving campus. If you are upgrading a current Mnova version, the old version need not be removed. In your current Mnova program, go to File, Help, Check for Updates, and proceed. Activate the new licenses as described below in section 6. Otherwise, to obtain your own copy of the 5 Mnova NMR licenses and the Mnova software, follow these instructions carefully.

  1. First, be sure you are a registered user of the Illinois Box system at https://box.illinois.edu/
  2. Then, go to this link, download, and save all 5 licenses to a known location on your computer: https://uofi.app.box.com/v/scs-nmr-mnova You will need to log in with your Net ID and password from a campus-secured website. You might need to copy and paste this link, or type the link to get it to work properly, or save this PDF letter separately and open the link via Adobe. Save all 5 licenses to your Downloads folder or other convenient, known location. It is acceptable that someone emails you all 5 licenses.
  3. Go to this link to download Mnova NMR version 15.0.1 software for your computer. https://mestrelab.com/download/mnova/ Click and save to the default location it creates on your computer. On a Windows PC the Programs Files/Mestrelab S.L folder will be about 1.18 GB. Again, use version 15.0.1. This version and license set are compatible with MacOS Big Sur.
    • If necessary, scroll down on the web site to “Download previous versions” and click on “15.0.1” and download the version appropriate for your computer.
  4. Once the software download is completed, locate the MestReNova-15.0.1-***_x64.msi file, Run it, and proceed to install. 
    1. Press Next when ready to proceed, then continue with the installation. If necessary, scroll down on the web site to “Download previous versions” and click on “15.0.1” and download the version appropriate for your computer. 
    2. If you are simply updating an existing version, you need not un-install the old version. i. In the Mnova window: File, Help, Check for Updates, Yes, Save file …
    3. Prediction and qNMR are both included in Mnova 15.0.1.
  5. License activation has some restrictions:
    1. The best way to activate the licenses is to open the Mnova software while using a wired Internet connection on campus.
    2. You cannot be connected to the campus unsecured WiFi network to activate the licenses. You might be able to use a secured connection such as IllinoisNet Secure Wireless Service (https://techservices.illinois.edu/services/wireless/our-wireless-networks )
    3. If you activate the licenses from off campus, you must use the campus VPN so you have a secured campus connection. 
    4. You can also install the VPN and use it regardless of the campus network you are on, and that should allow you to activate the licenses.
  6. Open the Mnova NMR software, and it will instruct you on how to activate the 5 licenses. If it does not instruct you, do this:
    1. Double click on Licenses (lower right), press Install, then follow the instructions and direct it to license 1, etc. Repeat the license installation step for each of the 5 licenses. 
    2. Once you activate all 5 licenses, restart Mnova and the software should be ready to use. It should open without any licensing errors. You can proceed to use the Mnova software even when not connected to the Internet (though on-line support features will not work).

On-line tutorials are built-in for nearly every feature of the Mnova software via File (upper left), Help, Download Examples. Also, File, Help, Help, Contents, Search tab, then type in a key word. The on-line manual for Mnova is here, but the 15.0.1 version is 1011 pages long.

Common problems:

  • Installation will not succeed if only part of the Mnova program has been downloaded. A Wi-Fi download might be incomplete. If needed, download using a wired connection, or ask for a copy from a friend via a USB stick. o The key directory created is Mestrelab Research S.L
  • If license activation is attempted while not on a secured, campus network, the program will not run. Again, a wired connection seems most reliable, and look for https:// in the web address.
  • As a reminder, download version 15.0.1. Free updates for us expire 25 April 2025.

Here is a more detailed Mnova NMR installation description: https://answers.uillinois.edu/scs/mnova

Here’s a basic, good tutorial on Mnova NMR: https://uofi.app.box.com/file/756702934725?s=136x7d7i3fzq5fbvgdokq2m4z9u2qiph

Best regards,

Dean Olson on behalf of the NMR Lab Staff:

Nikki Duay, Lingyang Zhu, Collette Xu; Zion Odoh, Richard Nong: Undergrad Cryogen Technical Assistants

Troubleshooting

  • Software does not load properly AND the Registration Wizard does not appear
    • Your license files may be properly added, but may not be valid for this version.  You should download and install the newest license files. 
    • Click on File > Help, then click on the box next to License Manager.
    • Click on the "Shopping Cart" icon and the "Registration Wizard" will appear.
    • Go back to Step 3 to download the newest license files, and proceed through the remaining instructions. 

  • The software will not check out a license:
    • Be sure you are connected to a University network.  This includes:
      • A wired connection inside a University of Illinois building
      • A wireless connection to IllinoisNet
        • IMPORTANT NOTE: If you are connected to "IllinoisNet_Guest", then you must also use the University's VPN. The wireless network "IllinoisNet_Guest" is not behind the University's firewall so without the VPN your computer will not be able to contact the license server.
      • A connection to the University's VPN
  • If you recently upgraded your operating system and the Mnova software will not load
    • Try downloading and installing the newest version of Mnova software. You do not need to uninstall the old version before installing the new version.

Tutorials

 



Keywords:
Mnova NMR software license mestrenova mestre 
Doc ID:
129575
Owned by:
Nikki D. in School of Chemical Sciences
UIUC
Created:
2023-07-06
Updated:
2025-06-23
Sites:
University of Illinois School of Chemical Sciences